🚨 A new twist in #NLRbiology! 🚨
— Tarhan Ibrahim (@TarhanEI) September 23, 2024
Excited to report on the surprising mechanism where the helper NLR NRG1 targets organellar membranes to trigger immunity unlike canonical CC-NLRs, which function at the plasma membrane!
1/11 🧵https://t.co/jqIquRcz9D pic.twitter.com/2JpervDGcb
Our new paper is out: surface immune signalling can unlock an NLR immune receptor through alternative splicing. In potato Rpi-vnt1.1, splicing removes an N-terminal “safety cap”, priming the receptor for resistosome assembly and defence. https://t.co/9Y8v49Vb84 pic.twitter.com/F60gE2rjV6
— Tolga Bozkurt (@Tolga_Bzkrt) July 6, 2026
Mind the GAP-New research alert!🚨Our latest study revealed the first known case of a pathogen effector targeting a RabGAP! 🦠The effector remodels the pathogen interface and suppresses defense-related secretion mediated by its cognate Rab.🌱🚦#research https://t.co/LCx2FbbMtP pic.twitter.com/KmJL2cQNZ3
— Enoch Lok Him Yuen (@EnochYuen) January 15, 2024